A diagnostic model based on DNA methylation haplotype block characteristics for identifying papillary thyroid carcinoma from thyroid adenoma

In this study, we aimed to develop and validate a diagnostic model for PTC based on DNA methylation markers. A total of 142 thyroid nodule tissue samples containing 84 cases of PTC and 58 cases of thyroid adenoma (TA) were collected for reduced representation bisulfite sequencing (RRBS) and subsequent analysis.

Source: Translational Research - October 18, 2023 Category: Research Authors: Dong Xu, Yi Lai, Hongmei Liu, He Li, Ningning Feng, Yiying Liu, Chengxiang Gong, Yunzhi Zhang, Jiaqing Zhou, Yuling Shen Source Type: research