HMGB1 Release Induced by EV71 Infection Exacerbates Blood-Brain Barrier Disruption via VE-cadherin Phosphorylation

CONCLUSION: The inflammatory mediator HMGB1 released by EV71 exacerbated BBB disruption by enhancing VE-cadherin phosphorylation, which in turn aggravated EV71-induced neuroinflammation.PMID:37832655 | DOI:10.1016/j.virusres.2023.199240

Source: Virus Research - October 13, 2023 Category: Virology Authors: Qiao You Jing Wu Ye Liu Fang Zhang Na Jiang Xiaoyan Tian Yurong Cai Enhui Yang Ruining Lyu Nan Zheng Deyan Chen Zhiwei Wu Source Type: research