M < sub > 4 < /sub > IDP stimulates ROS elevation through inhibition of mevalonate pathway and pentose phosphate pathway to inhibit colon cancer cells

This study revealed for the first time a possible mechanism of bisphosphonate-induced increase of ROS in malignant tumor cells. This is helpful for the development of new molecular therapeutic targets and can provide new ideas for the combined therapy of bisphosphonates in tumors.PMID:37838274 | DOI:10.1016/j.bcp.2023.115856

Source: Biochemical Pharmacology - October 14, 2023 Category: Drugs & Pharmacology Authors: Ying Peng Qing-Zhu Liu Dong Xu Jia-Yu Fu Li-Xia Zhang Ling Qiu Jian-Guo Lin Source Type: research