Is conditioned pain modulation (CPM) affected by negative emotional state?

DiscussionThese results suggest that heat/thermal CPM is resistant to this specific type of symbolic threat induction and further research is necessary to examine whether it is resistant to fearful states in general.SignificanceThe attempt of modulating heat conditioned pain modulation (CPM) by emotional threat (fear/anxiety state) failed. Thus, heat CPM inhibition again appeared resistant to emotional influences. Pain-related brain potentials proved to be more sensitive for CPM effects than subjective ratings.

https://onlinelibrary.wiley.com/doi/10.1002/ejp.2192?af=R

Source: European Journal of Pain - October 15, 2023 Category: Anesthesiology Authors: Claudia Horn ‐Hofmann, Lena Jablonowski, Melanie Madden, Miriam Kunz, Stefan Lautenbacher Tags: ORIGINAL ARTICLE Source Type: research