Illuminating HTLV 1-induced Adult T-cell Leukemia/Lymphoma transcriptomic signature: a systems virology approach

CONCLUSIONS: In this study, we performed a deep bioinformatic examination on a limited set of genes with high probabilities of involvement in the pathogenesis of ATLL. Our results highlighted signaling pathways and genes with potential key roles in disease formation and resistance against current treatment strategies. Further studies are required to test the possible benefits of highlighted genes as biomarkers and targets of treatment.PMID:37832654 | DOI:10.1016/j.virusres.2023.199237
Source: Virus Research - Category: Virology Authors: Source Type: research