REM Behavior Disorder: Implications for PD Therapeutics

This article reviews RBD, its treatments, and implications for PD therapeutics.Recent FindingsRecent research recognizes RBD as a prodromal marker of PD, resulting in expansion of basic science and clinical investigations of RBD. Current basic science research investigates the pathophysiology of RBD and explores animal models to allow therapeutic development. Clinical research has focused on natural history observation, as well as potential RBD treatments and their impact on sleep and phenoconversion to neurodegenerative disease.SummaryRBD serves as a fresh access point to develop both neuroprotective and symptomatic therapies in PD. These types of investigations are novel and will benefit from the more established basic science infrastructure to develop new interventions.
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research