Hypophysitis Induced by Sintilimab in the Treatment of Bladder Cancer: A Case Report

CONCLUSION: Immunotherapy-induced hypophysitis (IH) can result in a severe adrenal crisis, and prompt recognition and diagnosis are crucial. Clinicians must remain vigilant for the possibility of IH in patients who exhibit recurrent fever, anorexia, cognitive decline, and personality changes following ICI treatment. It is imperative to consider this diagnosis early to initiate appropriate management promptly.PMID:37818555 | DOI:10.2174/0118715303257557231002064417
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Endocrinology Authors: Source Type: research