Efficacy and Safety of Esaxerenone in Hypertensive Patients with Diabetes Mellitus Undergoing Treatment with Sodium-Glucose Cotransporter  2 Inhibitors (EAGLE-DH)

ConclusionEsaxerenone effectively lowered BP, was safe, and showed renoprotective effects in hypertensive patients with diabetes mellitus receiving treatment with SGLT2 inhibitors. Esaxerenone and SGLT2 inhibitors did not interfere with either drug ’s efficacy and may reduce the frequency of serum potassium elevations, suggesting they are a compatible combination.Clinical Trial RegistrationjRCTs031200273.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research