Recombinant human diamine oxidase prevents hemodynamic effects of continuous histamine infusion in guinea pigs

ConclusionsProphylactic infusion of rhDAO_mHBM prevents hemodynamic effects in a guinea pig model of continuous histamine infusion. These findings might help in the translation from animals to humans and in the selection of the optimal dosing of rhDAO_mHBM during human histamine challenge studies.
Source: Inflammation Research - Category: Research Source Type: research