Exploring the role of insulin-like growth factor binding protein-1 in identifying idiopathic multicentric Castleman's disease types: Implications for the mTOR signaling pathway

CONCLUSION: The mTOR pathway is suggested to be activated in iMCD-TAFRO compared to iMCD-NOS, which may elevate the protein IGFBP-1. This protein may be a biomarker to distinguish iMCD-TAFRO from iMCD-NOS.PMID:37778714 | DOI:10.1016/j.clim.2023.109798

Source: Clinical Immunology - October 1, 2023 Category: Allergy & Immunology Authors: Remi Sumiyoshi Tomohiro Koga Shoichi Fukui Kaori Furukawa Mamiko Momoki Kunihiro Ichinose Shingo Yano Atsushi Kawakami Source Type: research