Low incidence of severe acute and chronic graft-versus-host disease in a long-term retrospective study with ATG Grafalon routine use

AbstractSince 2006, combined graft-versus-host disease (GVHD) prophylaxis with ATG Grafalon has been our department ’s base of peri-transplant supportive care. This recent retrospective study included 398 patients who underwent their first allogeneic hematopoietic stem cell transplantation after receiving a defined dose of ATG Grafalon. Our observations recorded reduced incidence of severe acute and chronic GVH D without negative impact on overall survival in a nonselected group with standard and uniform GVHD prophylaxis.
Source: Annals of Hematology - Category: Hematology Source Type: research