Potential involvement of IL-32 in cell-to-cell communication between macrophages and hepatoblastoma

ConclusionIL-32 was detected in hepatoblastoma cell lines, but not in all hepatoblastoma patients. We hypothesized that stimulation such as chemotherapy might induce expression of IL-32, which might be a critical mediator of chemoresistance in hepatoblastoma through inducing protumor activation in macrophages.
Source: Pediatric Surgery International - Category: Surgery Source Type: research