Platelet-Mediated Transfer of Cardioprotection by Remote Ischemic Conditioning and Its Abrogation by Aspirin But Not by Ticagrelor

ConclusionPlatelets serve as carriers for RIC ’s cardioprotective signal through an aspirin-sensitive and thus cyclooxygenase-dependent mechanism. The P2Y12 inhibitor ticagrelor per se induces a humoral cardioprotective signal.Graphical abstract
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research