Effect of dolutegravir on folate, vitamin B12 and mean corpuscular volume levels among children and adolescents with HIV: a sub-study of the ODYSSEY randomized controlled trial

CONCLUSIONS: Plasma and RBC folate levels were higher in children and adolescents receiving dolutegravir-based ART than on other ART regimens. Further studies are needed to clarify the mechanisms of these interactions and the clinical implications of increased blood folate levels.PMID:37766505 | PMC:PMC10534059 | DOI:10.1002/jia2.26174

Source: Journal of the International AIDS Society - September 28, 2023 Category: Infectious Diseases Authors: Linda Namutebi Barlow-Mosha Grace Miriam Ahimbisibwe Elizabeth Chappell Pauline Mary Amuge Annet Nanduudu Elizabeth Kaudha Timothy Amukele David Balamusani Bosco Kafufu Audrey Nimwesiga Hajira Kataike Rosemary Namwanje Gladys Kasangaki Alice Mulindwa Gera Source Type: research