Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students

Molecular genetic analysis of polymorphic variants of serotonin receptor genes (HTR2C andHTR2A) was performed in 89 healthy medical students and regulatory and adaptive capacities were determined by cardiorespiratory synchronism. The relationship of serotonin receptor gene polymorphisms and the regulatory and adaptive capabilities of the body were revealed. The highly active *G allele and *G/*G genotype of the serotonin receptorHTR2C gene and the heterozygous *A/*G genotype of the serotonin receptorHTR2A gene are associated with “good” regulatory and adaptive capacities. The low-active *C allele of the serotonin receptorHTR2C gene is associated with “low” regulatory and adaptive capacities.
Source: Bulletin of Experimental Biology and Medicine - Category: Biology Source Type: research