Incongruence between transcriptional and vascular pathophysiological cell states

This study shows incongruence between single-cell transcriptional states, vascular phenotypes and related pathophysiology. Our findings also suggest that the vascular structure abnormalization, rather than neoplasms, causes the reported anti-Dll4 antibody toxicity.PMID:37745941 | PMC:PMC7615119 | DOI:10.1038/s44161-023-00272-4

Source: Genomics Proteomics ... - September 25, 2023 Category: Genetics & Stem Cells Authors: Macarena Fern ández-Chacón Severin M ühleder Alvaro Regano Lourdes Garcia-Ortega Susana F Rocha Carlos Torroja Maria S Sanchez-Mu ñoz Mariya Lytvyn Ver ónica Casquero-Garcia Macarena De Andr és-Laguillo Lars Muhl Michael M Orlich Konstantin Gaengel Source Type: research