Sleep Spindle Generation Before and After Epilepsy Surgery: A Source Imaging Study in Children with Drug-Resistant Epilepsy

CONCLUSIONS: Our data indicate alterations in the EEG slow spindles after resective epilepsy surgery. Fast spindle generation on the contrary did not change after surgery. Although the study is limited by its retrospective nature, lack of healthy controls, and reduced cortical spatial sampling, our findings suggest a spatial relationship between the slow spindles and the epileptogenic generators.PMID:37737957 | DOI:10.1007/s10548-023-01007-1

Source: Brain Topography - September 22, 2023 Category: Neuroscience Authors: Assia Chericoni Lorenzo Ricci Georgios Ntolkeras Roberto Billardello Scellig S D Stone Joseph R Madsen Christos Papadelis P Ellen Grant Phillip L Pearl Fabrizio Taffoni Alexander Rotenberg Eleonora Tamilia Source Type: research