miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer ’s amyloidopathy

Studies of microglial gene manipulation in mouse models of Alzheimer ’s disease (AD) amyloidopathy can cause unpredictable effects on various key endpoints, including amyloidosis, inflammation, neuritic dystrop...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Tags: Correspondence Source Type: research