Eribulin promotes proliferation of CD8 < sup > + < /sup > T cells and potentiates T cell-mediated anti-tumor activity against triple-negative breast cancer cells

CONCLUSIONS: Eribulin promoted CD8+ T cell proliferation, repressed effector T cell differentiation, and harnessed T cell-mediated anti-tumor effects. These mechanisms may be one of the cues that eribulin can improve the immunological status of tumor-bearing hosts.PMID:37733186 | DOI:10.1007/s10549-023-07111-x

Source: Cell Research - September 21, 2023 Category: Cytology Authors: Tadafumi Shimizu Takaaki Oba Masanori Oshi Ken-Ichi Ito Source Type: research