CYP2D6 ‐guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial

ConclusionOur study revealed high acceptance of pharmacogenetic testing as part of a clinical trial among patients with cancer pain. However, provider response to genotype-guided recommendations was low, impacting assessment of pain-related outcomes. Addressing barriers to utility of pharmacogenetics results and clinical recommendations will be critical for implementation success.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 21, 2023 Category: Drugs & Pharmacology Authors: Scott A. Mosley, Emily Cicali, Alex Del  Cueto, Diane G. Portman, Kristine A. Donovan, Yan Gong, Taimour Langaee, Priya Gopalan, Jessica Schmit, Jason S. Starr, Natalie Silver, Young D. Chang, Sahana Rajasekhara, Joshua E. Smith, Heloisa P. Tags: RESEARCH ARTICLE Source Type: research