Drug repositioning of anti-microbial agent nifuratel to treat mast cell-mediated allergic responses

Conclusion: Our findings suggest that nifuratel inhibits pathways essential for the activation of mast cells to suppress anaphylaxis, thereby indicating that the anti-microbial drug, nifuratel, could be a potential drug candidate for IgE-mediated allergic disorders.PMID:37706235 | PMC:PMC10503296 | DOI:10.1177/03946320231202349
Source: International Journal of Immunopathology and Pharmacology - Category: Allergy & Immunology Authors: Source Type: research