Common changes in rat cortical gene expression after valproate or lithium treatment particularly affect pre- and post-synaptic pathways that regulate four neurotransmitters systems

CONCLUSIONS: Our study suggests that treating with mood stabilisers cause many common changes in levels of RNA which will impact on CNS function, particularly affecting post-synaptic muscarinic receptor functioning and the release of multiple neurotransmitters.PMID:37722808 | DOI:10.1080/15622975.2023.2258972
Source: The World Journal of Biological Psychiatry - Category: Psychiatry Authors: Source Type: research