Synthesis and anti-tumor activities in human leukemia-derived cells of polyenylpyrroles with a methyl group at the conjugated polyene terminus

This study provides useful structural information for designing novel drugs treating T-ALL and AML.PMID:37717362 | DOI:10.1016/j.bmcl.2023.129471

Source: Bioorganic and Medicinal Chemistry Letters - September 17, 2023 Category: Chemistry Authors: Tomoya Higashi Chihiro Yoshida Yoshifumi Hachiro Chihiro Nakata Azusa Takechi Takuya Yagi Kazuya Miyashita Nobuo Kitada Rika Obata Takashi Hirano Takahiko Hara Shojiro A Maki Source Type: research