Energy expenditure deficits drive obesity in a mouse model of Alstr öm syndrome

CONCLUSIONS: Either loss of ALMS1 causes a developmental delay in the mechanisms controlling early life EE or activation of compensatory mechanisms occurs after obesity is established in AS. Future studies will determine how ALMS1 modulates EE and how sex moderates this process.PMID:37712194 | DOI:10.1002/oby.23877

Source: Obesity - September 15, 2023 Category: Eating Disorders & Weight Management Authors: Erin J Stephenson Clint E Kinney Amanda S Stayton Joan C Han Source Type: research