Characterization of chemoresistant human non-small cell lung cancer cells by metabolic and lipidomic profiling

ConclusionsThis study reveals characteristic feature differences between drug-resistance NSCLC cells and their parental cells. We suggest potential therapeutic targets in chemoresistant NSCLC. Our results provide new insight into metabolic and lipidomic alterations in chemoresistant NSCLC. This could be used as fundamental information to develop therapeutic strategies for the treatment of chemoresistant NSCLC patients.
Source: Metabolomics - Category: Biology Source Type: research