The profile of adipokines associated with fibrosis and impaired microcirculation in systemic sclerosis

CONCLUSION: Adipsin may be considered a pivotal protein in the development of both fibrosis and impaired microcirculation. Its abnormal concentration reflects the intensity of skin thickening and the presence of pulmonary arterial hypertension. Adipsin, visfatin, and apelin are adipose tissue-derived molecules associated with digital vasculopathy.PMID:37696138 | DOI:10.1016/j.advms.2023.09.001
Source: Advances in Medical Sciences - Category: Biomedical Science Authors: Source Type: research