circEIF3I facilitates the recruitment of SMAD3 to early endosomes to promote TGF- β signalling pathway-mediated activation of MMPs in pancreatic cancer

Among digestive tract tumours, pancreatic ductal adenocarcinoma (PDAC) shows the highest mortality trend. Moreover, although PDAC metastasis remains a leading cause of cancer-related deaths, the biological mec...

Source: Molecular Cancer - September 9, 2023 Category: Cancer & Oncology Authors: Zhongjie Zhao, Wenbo Yang, Rui Kong, Yangyang Zhang, Le Li, Zengfu Song, Hongze Chen, Yan Luo, Tao Zhang, Chundong Cheng, Guanqun Li, Danxi Liu, Xinglong Geng, Hua Chen, Yongwei Wang, Shangha Pan & hellip; Tags: Research Source Type: research