Immunogenicity and protective efficacy of human metapneumovirus virus-like particles produced by a recombinant baculovirus in mice

CONCLUSIONS: This is the first study to demonstrate that HMPV VLP was successfully prepared in the baculovirus expression system. HMPV VLP could induce specific humoral and cellular immune responses as well as protective efficacy, and aluminum hydroxide may be an effective adjuvant in mice.PMID:37657510 | DOI:10.1016/j.virusres.2023.199215

Source: Virus Research - September 1, 2023 Category: Virology Authors: Fenlian Ma Aijun Chen Lihong Yao Hanchun Gao Qian Zhang Wenzhe Hou Lishu Zheng Source Type: research