Norepinephrine Promotes Neuronal Apoptosis of Hippocampal HT22 Cells by Up-regulating the Expression of Long Non-coding RNA MALAT1

In conclusion, high level of the stress-induced hormone NE promoted apoptosis of hippocampal neurons through elevating the expression of MALAT1. Our findings provide new experimental data supporting the epigenetic mechanisms in the regulation of stress response and may provide a potential therapeutic target for stress-related cognition dysfunction.PMID:37632346 | DOI:10.1080/10253890.2023.2252905

Source: Stress - August 26, 2023 Category: Research Authors: Ying Wang Hui Hu Yuhan Wu Yun Zhao Fang Xie Zhaowei Sun Xue Wang Lingjia Qian Source Type: research