A systematic review of contrast-enhanced computed tomography calcium scoring methodologies and impact of aortic valve calcium burden on TAVI clinical outcomes

This systematic review examines the role of aortic valve calcification (AVC) on transcatheter aortic valve implantation (TAVI) outcomes. Sixty-eight studies were included, reporting varied methodologies for quantifying AVC. AVC quantification methodology with contrast-enhanced CT was found to be variable. A positive association between calcium burden and increased risk of adverse outcomes, including permanent pacemaker implantation, paravalvular leak, and aortic rupture, was reported. AVC negatively impacts TAVI outcomes independently of the quantification method.

Source: Journal of Cardiovascular Computed Tomography - August 25, 2023 Category: Radiology Authors: Eduardo Flores-Umanzor, Rajesh Keshvara, Seleman Reza, Areeba Asghar, Mohammed Rashidul Anwar, Pedro L. Cepas-Guillen, Mark Osten, Jaydeep Halankar, Lusine Abrahamyan, Eric Horlick Tags: Review article Source Type: research