Tolerable treatment of glioblastoma with redox-cycling 'mitocans': a comparative study in vivo

Discussion: Q0/A differentiated cancer cells and tissues, particularly glioblastoma, from normal ones by redox targeting, causing a severe oxidative stress in the tumor but not in non-cancerous tissues. Q0/A had a pronounced anticancer activity and could be considered safe for the organism within certain concentration limits. The results suggest that the rate of tumor resorption and metabolism of toxic residues must be controlled and maintained within tolerable limits to achieve longer survival, especially at intracranial drug administration.PMID:37581329 | PMC:PMC10435007 | DOI:10.1080/13510002.2023.2220531
Source: Redox Report : communications in free radical research - Category: Biochemistry Authors: Source Type: research