Synergistic Effect of Naringin and Glimepiride in Streptozotocin-induced Diabetic Rats

Conclusion A synergistic effect of Naringin and glimepiride was observed during the estimation of various biochemical parameters like body weight, fasting blood sugar, creatinine, urine level, TG, total cholesterol, SGOT, SGPT, ALP, Insulin, HbA1C, antioxidant parameters like SOD, GSH, and catalase in STZ-induced diabetic rats. Further, the combination of therapy improves the protective effect of the pancreas, kidney, and liver, suggesting a potential antidiabetic effect.PMID:37592777 | DOI:10.2174/1573399820666230817154835
Source: Current Diabetes Reviews - Category: Endocrinology Authors: Source Type: research