Aberrant PI3K δ splice isoform as a potential biomarker and novel therapeutic target for endocrine cancers

ConclusionIn summary, our study has suggested a promising potential of utilizing PI3Kδ-S (an oncogenic isoform conferring drug resistance and exempt from PTEN regulation) as a prognostic biomarker and drug target in advanced endocrine cancers.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research