Protein Induced by Vitamin K Absence or Antagonist-II Versus Alpha-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma: A Systematic Review With Meta-Analysis

CONCLUSION: This study reveals that PIVKA-II is a promising biomarker for identifying and tracking HCC, exhibiting greater accuracy than AFP. Our findings indicate that PIVKA-II outperforms AFP in detecting HCC across diverse racial groups and sample sizes, as well as in cases of HBV-related, HCV-related, or mixed-etiology HCC.PMID:37575350 | PMC:PMC10416192 | DOI:10.14740/jocmr4951

Source: Clin Med Res - August 14, 2023 Category: Research Authors: Abdallah Kobeissy Nooraldin Merza Alsadiq Al-Hillan Safa Boujemaa Zohaib Ahmed Mohamad Nawras Mohammed Albaaj Dushyant Singh Dahiya Yaseen Alastal Mona Hassan Source Type: research