Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.

Obesity and type 2 diabetes impair SARS-CoV-2 mRNA vaccine efficacy in a murine model.

Source: Journal of Allergy and Clinical Immunology - August 16, 2023 Category: Allergy & Immunology Authors: Timothy R. O ’Meara, Etsuro Nanishi, Marisa E. McGrath, Soumik Barman, Danica Dong, Carly Dillen, Manisha Menon, Hyuk-Soo Seo, Sirano Dhe-Paganon, Robert K. Ernst, Ofer Levy, Matthew B. Frieman, David J. Dowling Source Type: research