Lipidomic analysis identifies long-chain acylcarnitine as a target for ischemic stroke

CONCLUSION: LCACs could accumulate and damage neurons by inducing astrocytic mitochondrial dysfunction in AIS. LCACs play a crucial role in the pathology of AIS and are novel promising diagnostic and prognostic biomarkers for AIS.PMID:37572732 | DOI:10.1016/j.jare.2023.08.007

Source: Cell Research - August 12, 2023 Category: Cytology Authors: Xin-Xin Huang Lei Li Run-Hao Jiang Jian-Bing Yu Yu-Qin Sun Jinjun Shan Jin Yang Juan Ji Shu-Qi Cheng Yin-Feng Dong Xi-Yue Zhang Hai-Bin Shi Sheng Liu Xiu-Lan Sun Source Type: research