CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation

ConclusionsOur results demonstrate that the improved functional outcome following cardiomyocyte transplantation is dependent on a specific CCR2 macrophage response. This work highlights the need to study the role of the immune response for cardiomyocyte cell therapy for successful clinical translation.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research