Overlapping Epstein-Barr virus encephalitis and autoimmune glial fibrillary acidic protein astrocytopathy

We describe three cases of overlapping Epstein-Barr virus (EBV) Encephalitis and Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP-A). The three cases all presented with initial symptoms of fever, headache, coma, and posture tremor of the upper limbs, then followed by limb weakness and dysuria. All of the three cases were on ventilators. Case 1 and 2 improved dramatically after intravenous methylprednisoloneand immunoglobulin treatment. However, case 3 presented dyspneic, and died from gastrointestinal hemorrhage.

Source: Journal of Neuroimmunology - August 7, 2023 Category: Allergy & Immunology Authors: Jin-ru Zhang, Sheng Zhuang, Xiao-dong Xu, Wen-li Song, Ke-ru Li, Yu Jiang, Xiao-yu Cheng, Ji-jun Shi, Wei-dong Hu, Chun-feng Liu, Yan-lin Zhang Tags: Short Communication Source Type: research