Cognitive behaviour therapy plus aerobic exercise training to increase activity in patients with myotonic dystrophy type 1 (DM1) compared to usual care (OPTIMISTIC): study protocol for randomised controlled trial
Discussion
OPTIMISTIC will not only provide effectiveness data on an intervention that could fill a treatment-gap for DM1 patients but will also improve our understanding of the relevant determinants of the prognosis of DM1.
Trial registration
Registration number: Cinicaltrials.gov NCT02118779; registered 11 April 2014.
Source: Trials - Category: Research Source Type: clinical trials