Multiple Injections of Adipose-Derived Stem Cells Improve Graft Survival in Human-to-Rat Skin Xenotransplantation through Immune Modulation

Conclusion:This study presented that triple injections of ADSCs appeared to be superior to a single injection in suppressing cell-mediated xenograft rejection. The immunomodulatory effects of ADSCs are associated with the downregulation of IFN- γ and upregulation of PGES in skin xenografts and lymph nodes.
Source: Tissue Engineering and Regenerative Medicine - Category: Biotechnology Source Type: research