Artificial Intelligence Assisted Repurposing of Lubiprostone Alleviates Tubulointerstitial Fibrosis.

In this study, we investigated the anti-fibrotic effect of the machine learning-based repurposed drug, Lubiprostone, validated through an advanced proximal tubule on a chip system and in vivo UUO mice model.

Source: Translational Research - August 2, 2023 Category: Research Authors: Anupama Samantasinghar, Faheem Ahmed, Chethikkattuveli Salih Abdul Rahim, Kyung Hwan Kim, Sejong Kim, Kyung Hyun Choi Source Type: research