Subjective and objective sleep alterations in medication-na ïve children and adolescents with autism spectrum disorder: a systematic review and meta-analysis

CONCLUSION: We found that medication-naïve children and adolescents with ASD presented significantly more subjective and objective sleep alterations compared to TD and identified possible moderators of these differences. Future research requires an analysis of how these sleep alterations are linked to core symptom severity and comorbid behavioural problems, which would provide an integrated therapeutic intervention for ASD. However, our results should be interpreted in light of the potential publication bias.PMID:37469173 | DOI:10.1017/S2045796023000574

Source: Epidemiology and Psychiatric Sciences - July 20, 2023 Category: Psychiatry Authors: Heeyeon Kim Jae Han Kim Junghwan Kim Jong Yeob Kim Samuele Cortese Lee Smith Ai Koyanagi Joaquim Radua Paolo Fusar-Poli Andre F Carvalho Gonzalo Salazar de Pablo Jae Il Shin Keun-Ah Cheon Marco Solmi Source Type: research