The Effect of Renal Replacement Therapy in a Patient with Mercaptopurine Toxicity: Time to Revise Guidelines

CONCLUSION: In this case of thiopurine toxicity, a patient with autoimmune hepatitis presents with abdominal pain, nausea, vomiting, and diarrhea. We show in this case report that renal replacement therapy had no effect on total body clearance of mercaptopurine.PMID:37455454 | DOI:10.2174/1574886318666230714105801

Source: Current Drug Safety - July 17, 2023 Category: Drugs & Pharmacology Authors: Quaedvlieg Hjl Polderman Fn Borkent M De Jonge Hjm Annema Pa Derijks Ljj Sikma Ma Bethlehem C Source Type: research