Diabetic Ketoacidosis Associated with Sodium-Glucose Cotransporter 2 Inhibitors: Clinical and Biochemical Characteristics of 29 Cases

CONCLUSIONS: The majority of SGLT2i-associated DKA cases occurred in patients with T2DM without prior episodes of DKA. The most common presenting symptoms were nausea, vomiting, and abdominal pain, while poor food intake and infection were the main precipitants. Clinicians should consider the possibility of DKA in SGLT2i-treated patients presenting with these symptoms, even in absence of marked hyperglycemia.PMID:37441367 | PMC:PMC10335870 | DOI:10.1155/2023/6615624

Source: International Journal of Endocrinology - July 13, 2023 Category: Endocrinology Authors: G A Stamatiades P D'Silva M Elahee G M Viana A Sideri-Gugger S K Majumdar Source Type: research