Investigation of Brain Iron in Niemann-Pick Type C: A 7T Quantitative Susceptibility Mapping Study [FUNCTIONAL]

CONCLUSIONS:
Our findings suggest iron deposition in the pulvinar nucleus in Niemann-Pick type C disease, which is associated with thalamic atrophy and disease severity. This preliminary evidence supports the link between iron and neurodegeneration in Niemann-Pick type C, in line with existing literature on other neurodegenerative disorders.

Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Ravanfar, P., Syeda, W. T., Rushmore, R. J., Moffat, B., Lyall, A. E., Merritt, A. H., Devenyi, G. A., Chakravarty, M. M., Desmond, P., Cropley, V. L., Makris, N., Shenton, M. E., Bush, A. I., Velakoulis, D., Pantelis, C., Walterfang, M. Tags: FUNCTIONAL Source Type: research