CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma

The majority of patients with recurrent or metastasized head and neck squamous cell carcinoma (HNSCC) do not benefit from immune checkpoint blockade (ICB) while several patients experience severe and persisten...

Source: Clinical Epigenetics - July 6, 2023 Category: Research Authors: Friederike Hoffmann, Alina Franzen, Luka de Vos, Lennert Wuest, Zs ófi Kulcsár, Simon Fietz, Alexander Philippe Maas, Sarah Hollick, Marie Yatou Diop, Jennis Gabrielpillai, Timo Vogt, Pia Kuster, Romina Zarbl, Joern Dietrich, Glen Kristiansen, Peter Bro Tags: Research Source Type: research