Hyperoside ameliorates cerebral ischaemic-reperfusion injury by opening the TRPV4 channel < em > in  vivo < /em > through the IP < sub > 3 < /sub > -PKC signalling pathway

CONCLUSIONS: Although Hyp showed protective effect in ischaemic stroke, more clinical trial certification is needed due to the difference between animals and humans.PMID:37410551 | DOI:10.1080/13880209.2023.2228379

Source: Pharmaceutical Biology - July 6, 2023 Category: Drugs & Pharmacology Authors: Lei Shi Chenchen Jiang Hanghang Xu Jiangping Wu Jiajun Lu Yuxiang He Xiuyun Yin Zhuo Chen Di Cao Xuebin Shen Xuefeng Hou Jun Han Source Type: research