161Tb-DOTATOC Production Using a Fully Automated Disposable Cassette System: A First Step Toward the Introduction of 161Tb into the Clinic

Conclusion: The current study demonstrated that 161Tb has appropriate features for clinical use. The developed synthesis protocol guarantees high yields and safe preparation of injectable 161Tb-DOTATOC. The investigated approach could be translated to other DOTA-derivatized peptides; thus, 161Tb could be successfully applied in clinical practice for radionuclide therapy.

Source: Journal of Nuclear Medicine - June 30, 2023 Category: Nuclear Medicine Authors: Favaretto, C., Grundler, P. V., Talip, Z., Landolt, S., Sepini, L., Koster, U., Muller, C., Schibli, R., Geistlich, S., van der Meulen, N. P. Tags: Clinical Investigations Source Type: research