JAK2 V617F Mutation and Large Cerebral Artery Disease in Patients with Myeloproliferative Neoplasms

CONCLUSIONS: This study revealed a significant association between the JAK2 V617F mutation and LCAD in patients with MPNs. This suggests that the JAK2 V617F mutation may promote cerebrovascular atherosclerosis and could be very important in determining therapeutic strategies for patients with not only JAK2 V617F-mutated MPNs but also LCAD-related stroke.PMID:37344447 | DOI:10.5551/jat.64118

Source: Journal of Atherosclerosis and Thrombosis - June 21, 2023 Category: Cardiology Authors: Naoki Oyama Takanori Iwamoto Keito Doyu Saki Miyazato Tomoko Okazaki Seiko Yamada Toshinori Kondo Hideho Wada Yoshiki Yagita Source Type: research