Comparison of intravenous paracetamol (acetaminophen) to intravenously or intramuscularly administered non-steroidal anti-inflammatory drugs (NSAIDs) or opioids for patients presenting with moderate to severe acute pain conditions to the ED: systematic review and meta-analysis
Conclusion
In patients presenting to the ED with a diverse range of pain conditions, IVP provides similar levels of pain relief compared with opiates/opioids or NSAIDs at T30 post administration. Patients treated with NSAIDs had lower risk of rescue analgesia, and opioids cause more AEs, suggesting NSAIDs as the first-choice analgesia and IVP as a suitable alternative.
PROSPERO registration number
CRD42021240099.
Source: Emergency Medicine Journal - Category: Emergency Medicine Authors: Qureshi, I., Abdulrashid, K., Thomas, S. H., Abdel-Rahman, M. E., Pathan, S. A., Harris, T. Tags: Systematic review Source Type: research
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